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While most of the selected texts belong to original articles,
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institución:(a) Department of Pediatrics, The University of Alberta, Edmonton, Alberta, Canada. (b) KidClot Program, Stollery Children's Hospital, Alberta Health Services, Edmonton, Alberta, Canada.
Extracto:
This article summarizes
the milestones in the development of tapinarof cream 1% leading to this first
pediatric approval.
Cita:Paediatr Drugs 2025 Mar 29;
Autor/es:This article summarizes
the milestones in the development of tapinarof cream 1% leading to this first
pediatric approval.
institución:This article summarizes
the milestones in the development of tapinarof cream 1% leading to this first
pediatric approval.
Conflicto:Declarations. Funding: The preparation of this review was not supported by any external funding. Authorship and Conflict of Interest: During the peer review process the manufacturer of the agent under review was offered an opportunity to comment on the article. Changes resulting from any comments received were made by the authors on the basis of scientific completeness and accuracy. Sheridan...
M. Hoy is a salaried employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. All authors contributed to this article and are responsible for its content. Ethics Approval, Consent to Participate, Consent to Publish, Availability of Data and Material, Code Availability: Not applicable.
Effectiveness of dexmedetomidine as a premedication for pediatric patients undergoing outpatient dental surgery under general anaethesia-systematic review and meta-analysis.
Effectiveness of dexmedetomidine as a premedication for pediatric patients undergoing outpatient dental surgery under general anaethesia-systematic review and meta-analysis.
Fuente:Peerj
Extracto:
However, high-quality clinical trials with larger sample sizes are needed to
determine the selection of different medication modes and doses, as well as to
study perioperative adverse reactions.
Claves:Child, Emergence delirium, General anesthesia, Sedation
Cita:PeerJ 2025; 13 : e19216.
Autor/es:Zhang, Xiao (a) Fan, Ze (b)
institución:(a) State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Anesthesiology, School of Stomatology, Fourth Military Medical University, Xi'an, Shaanxi, China. (b) State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Anesthesiology, School of Stomatology, Fourth Military Medical University, Xi'an, Shaanxi, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan. (b) Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan. nnishio23@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Newly designed amplicons-based method for near-full-length genome (NFLG) sequencing of HIV-1 group M recombinant forms.
Newly designed amplicons-based method for near-full-length genome (NFLG) sequencing of HIV-1 group M recombinant forms.
Fuente:Molecular Biology Reports
Tipo de trabajo:Consenso
Extracto:
In summary, we describe a methodology for HIV-1 NFLG
sequencing, which is based on partially overlapping, multiple PCR fragments,
spanning the HIV-1 genome. Additionally, this newly refined method was compared
to HIV-1 NFLG results of PCR-free metagenomic sequencing and proved to obtain
greater coverage of the HXB2 reference genome. Yet, further testing and
validation on a larger cohort is required. Still, this method enables sequencing
of 20 different patient samples in a single MiSeq sequencing run and was used for
the characterization of different HIV-1 RFs and pure subtypes circulating in
Israel.
Claves:Circulating recombinant forms (CRFs), HIV, HIV near-full length genome (NFLG) sequencing, HIV-1, Illumina miseq, Metagenomics, Next generation sequencing (NGS)
Cita:Mol Biol Rep 2025 Apr 4; 52 (1) : 362.
Autor/es:Moscona, Roy (a) Wagner, Tali (b)
institución:(a) Central Virology Laboratory, Ministry of Health, Public Health Services, The Chaim Sheba Medical Center, Tel HaShomer, Ramat gan, Israel. roymosc@post.bgu.ac.il. (b) Division of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH, USA. roymosc@post.bgu.ac.il.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Supportive care in cancer official journal of the Multinational Association of Supportive Care in Cancer
Selección SIIC: 10 Abril, 2025
Supportive care in cancer official journal of the Multinational Association of Supportive Care in Cancer
Practice patterns in the diagnosis and management of chemotherapy-induced peripheral neuropathy in adolescents and young adults with cancer: a survey of oncologists.
Practice patterns in the diagnosis and management of chemotherapy-induced peripheral neuropathy in adolescents and young adults with cancer: a survey of oncologists.
Fuente:Supportive Care in Cancer Official Journal of The Multinational Association of Supportive Care in Cancer
Extracto:
Our survey suggests a broad spectrum
of CIPN management in AYAs with cancer. The heterogenicity in practices and
significant differences between pediatric and medical oncologists underscores an
urgent need to better understand the source of heterogeneity in CIPN management
practices and barriers to evidence-based care delivery.
Claves:Adolescent young adult, Pediatric oncology, Peripheral neuropathy, Supportive care
Cita:Support Care Cancer 2025 Apr 4; 33 (4) : 350.
Autor/es:Belsky, Jennifer A (a) Dupuis, L Lee (b)
institución:(a) Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA. Jbelsky@iu.edu. (b) Department of Pharmacy, Leslie Dan Faculty of Pharmacy, Research Institute, the Hospital for Sick Children, University of Toronto, Toronto, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Implementation of an Organization-Based Couples Health Promotion Program to Improve Physician Well-Being.
Implementation of an Organization-Based Couples Health Promotion Program to Improve Physician Well-Being.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND RELEVANCE: In this cohort study of
an organizationally sponsored intervention consisting of a couples' workshop
designed to mitigate the adverse IWPR for physicians, participation was
associated with statistically significant improvements in IWPR, burnout, and
self-valuation. Further development of interventions to mitigate adverse IWPR
among physicians is warranted.
Cita:JAMA Netw Open 2025 Apr 1; 8 (4) : e253218.
Autor/es:Gold, Jessica M (a) Shanafelt, Tait D (b)
institución:(a) Department of Pediatrics, Stanford University School of Medicine, Stanford, California. (b) Department of Internal Medicine, Stanford University School of Medicine, Stanford, California.
Conflicto:Conflict of Interest Disclosures: Dr Gold reported grants from the University of California, San Diego T. Denny Sanford Institute for Empathy and Compassion during the conduct of the study. Dr Shanafelt reported a patent for Well-Being Index and Mayo Leader Index with royalties paid from Mayo Clinic. Dr Shanafelt is coinventor of the Well-being Index instruments and the Leadership Index....
Mayo Clinic holds the copyright for these instruments and has licensed them for use outside of Mayo Clinic. Mayo Clinic pays Dr Shanafelt a portion of any royalties received; and as an expert on the well-being of health care professionals, Dr. Shanafelt frequently gives grand rounds/key note lecture presentations and provides advising for health care organizations. He receives honoraria for some of these activities. Dr Trockel reported grants from Center for Research on Empathy and Compassion, University of California, San Diego during the conduct of the study and personal fees from Marvin Behavioral Health outside the submitted work. No other disclosures were reported.
Exploring the mechanism of Pujin oral liquid in the treatment of preterm white matter injury using network pharmacology and molecular docking.
Exploring the mechanism of Pujin oral liquid in the treatment of preterm white matter injury using network pharmacology and molecular docking.
Fuente:Medicine
Extracto:
Its clinical application in treating preterm white matter injuries
is promising.
Cita:Medicine (Baltimore) 2025 Jan 3; 104 (1) : e40799.
Autor/es:Gong, Xing-Ruo (a) You, Xiao-Rui (b)
institución:(a) Department of Pediatrics, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China. (b) Hebei University of Chinese Medicine, Shijiazhuang, Hebei Province, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Quality management for nurses performance and commitment on government hospitals: A cross-sectional study.
Quality management for nurses performance and commitment on government hospitals: A cross-sectional study.
Fuente:Medicine
Extracto:
Stakeholders should strengthen continued education to nurses
and stimulate their love of the nursing profession.
Cita:Medicine (Baltimore) 2025 Jan 3; 104 (1) : e40085.
Autor/es:Alzoubi, Majdi M (a) Al-Mugheed, Khalid (b)
institución:(a) Faculty of Nursing, Al-Zaytoonah University of Jordan, Amman, Jordan. (b) College of Nursing, Riyadh Elm University, Riyadh, Saudi Arabia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Experience in the treatment of giant orbital intraconal teratoma
Experience in the treatment of giant orbital intraconal teratoma
Fuente:Medicine
Tipo de trabajo:Caso clínico
Extracto:
The findings emphasize the importance
of timely implantation into the orbital after mass excision to enhance orbital
volume and reduce the incidence of complications.
Cita:Medicine (Baltimore) 2025 Jan 3; 104 (1) : e41205.
Autor/es:Li, Ruimiao (a) Ren, Mingyu (b)
institución:(a) Department of Orbital Disease and Ocular Tumor, Hebei Eye Hospital, Xingtai, Hebei, China. (b) Department of Orbital Disease and Ocular Tumor, Hebei Eye Hospital, Xingtai, Hebei, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The emergence of academic pediatric acute and urgent care fellowships: entrustable professional activities.
The emergence of academic pediatric acute and urgent care fellowships: entrustable professional activities.
Fuente:Medical Education Online
Tipo de trabajo:Consenso
Extracto:
): PAC-specific EPAs focusing on
clinical excellence, procedural competence, and high-quality care were all deemed
essential components for PAC fellowships. Delineation of these EPAs will be
critical to guide development of fellowship curricula.
Claves:Pediatric urgent care, entrustable, medical education, medical fellowship, pediatric acute care, postgraduate training, professional activities
Cita:Med Educ Online 2025 Dec; 30 (1) : 2485503.
Autor/es:Shaukat, Haroon (a) Berkowitz, Deena (b)
institución:(a) Department of Emergency Medicine, Children's National Medical Center, Washington, DC, USA. (b) Department of Pediatrics, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Conflicto:No potential conflict of interest was reported by the author(s).
Maternal nutrition literacy and childhood obesity in food-insecure and secure households.
Maternal nutrition literacy and childhood obesity in food-insecure and secure households.
Fuente:Scientific Reports
Extracto:
The findings suggest that nutrition education programs may be
particularly beneficial for children living in food-insecure households, and that
these programs should be tailored to address the specific needs of this
population.
Claves:Childhood obesity, Cross-sectional study, Food and nutrition literacy, Food-insecurity, Health improvement, Iran, Nutrition knowledge
institución:(a) Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. (b) Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Pediatric Surgery, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China. (b) Department of Pediatrics, Qilu Hospital of Shandong University, Jinan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Significance of busulfan administration route including therapeutic drug monitoring in the conditioning regimen of pediatric patients prior to hematopoietic stem cell transplantation.
Significance of busulfan administration route including therapeutic drug monitoring in the conditioning regimen of pediatric patients prior to hematopoietic stem cell transplantation.
Fuente:Journal of Cancer Research and Clinical Oncology
Extracto:
In this study, we demonstrate that
patients with i.v. administration of busulfan with TDM had a significantly lower
rate of TRM and a significantly improved OS compared to patients who received
i.v. administration of busulfan without TDM, who, in turn, had a better outcome
than patients with oral busulfan administration. Additionally, these data
emphasize the clinical relevance of AUC measurements in patients with malignant
diseases to prevent hepatic SOS.
Cita:J Cancer Res Clin Oncol 2025 Apr 4; 151 (4) : 132.
Autor/es:Hämmerle, Stephanie (a) Ernst, Jana (b)
institución:(a) Department of Pediatrics, Jena University Hospital, Am Klinikum 1, 07747, Jena, Germany. (b) Department of Pediatrics, Jena University Hospital, Am Klinikum 1, 07747, Jena, Germany.
Conflicto:Declarations. Conflict of interest: The authors declare that they have no conflict of interest. Ethical approval: All procedures were in accordance with the ethical standards. The study has been approved by the Jena University Hospital Ethics Committee (2023–3158). Informed consent was obtained from all individual participants or the responsible persons included in the study.
Different risk factors for elevated blood pressure according to abdominal obesity in overweight children and adolescents.
Different risk factors for elevated blood pressure according to abdominal obesity in overweight children and adolescents.
Fuente:Bmc Pediatrics
Tipo de trabajo:Guía
Extracto:
In children with overweight or obesity, the risk factors
for EBP-HTN vary depending on the presence of abdominal obesity. These findings
highlight the need for differentiated surveillance and prevention strategies
based on abdominal obesity status in this high-risk population. CLINICAL TRIAL
NUMBER: Not applicable.
institución:(a) Department of Pediatrics, Ajou University Hospital, Ajou University School of Medicine, Suwon, Republic of Korea. (b) Department of Statistical Data Science, University of Seoul, Seoul, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Associations between amino acid levels and autism spectrum disorder severity.
Associations between amino acid levels and autism spectrum disorder severity.
Fuente:Bmc Psychiatry
Extracto:
This
study identifies potential amino acid biomarkers that may contribute to ASD
severity assessment. Further research is needed to validate these findings and
explore their clinical utility.
institución:(a) Department of Pediatrics, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, 450000, China. (b) School of Pediatric Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Treatment and prognosis of pelvic-related urethral injuries in children
Treatment and prognosis of pelvic-related urethral injuries in children
Fuente:Bmc Pediatrics
Tipo de trabajo:Revisión sistemática
Extracto:
There was no difference in
complications between the two surgical modalities at long-term follow-up,
however, PR presents more advantages in reduce operative times, frequency of
postoperative infections, cost, and long-term quality of life. CLINICAL TRIAL
NUMBER: Not applicable.
institución:(a) Department of Urology Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Chongqing, China. (b) Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Chongqing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effectiveness of second step program in fostering social-emotional skills in young children: a study in Japan.
Effectiveness of second step program in fostering social-emotional skills in young children: a study in Japan.
Fuente:Bmc Pediatrics
Extracto:
The social-emotional learning Second Step program
implemented on a classroom basis may be effective in early childhood. An early
approach targeting kindergarten-aged children is necessary to prevent school
maladjustment.
Claves:Children, Japan, Second step, Social-emotional skills
Cita:BMC Pediatr 2025 Apr 4; 25 (1) : 276.
Autor/es:Hosokawa, Rikuya (a) Tomozawa, Riho (b)
institución:(a) Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Shogoin-kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. hosokawa.rikuya.4r@kyoto-u.ac.jp. (b) Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Shogoin-kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
Maximizing the checklist's full
potential requires continuous efforts, including sustained support, regular
audit, and strong commitment from all stakeholders.Recommendation Policymakers,
healthcare administrators, and surgical teams must work together to integrate the
checklist into routine workflows, ensure continuous monitoring and support, and
foster a culture of safety to improve patient outcomes.
Claves:Barrier, Completeness, Compliance, Systematic review, World health organization surgical safety checklist
Cita:BMC Health Serv Res 2025 Apr 4; 25 (1) : 504.
institución:(a) Department of Nursing, College of Health Sciences, Woldia University, Woldia, Ethiopia. tesfayeengdaw@gmail.com. (b) Department of Public Health, College of Health Sciences, Woldia University, Woldia, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
